top of page
The Sound of Evolution
Delafloxacin
Mechanism of action:
Delafloxacin is a fluoroquinolone antibiotic. Delafloxacin inhibits bacterial DNA gyrase (bacterial topoisomerase II) and topoisomerase IV, interfering with DNA replication, transcription, repair, and segregation, ultimately leading to bacterial death.
Reference(s):
Rang HP et al. (2012). Rang and Dale's Pharmacology (7th ed., pp. 612–614). Elsevier/Churchill Livingstone.
bottom of page