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The Sound of Evolution
Tenecteplase
Mechanism of action:
Tenecteplase is a tissue plasminogen activator. It converts fibrin-bound plasminogen into active plasmin, which degrades fibrin within blood clots.
Reference(s):
1. Gurbel PA et al. (2005). The platelet-related effects of tenecteplase versus alteplase versus reteplase. Blood Coagul Fibrinolysis.
2. Melzer C et al. (2004). Tenecteplase for the treatment of massive and submassive pulmonary embolism. J Thromb Thrombolysis.
3. Ohman EM et al. (2005). Tenecteplase and tirofiban in ST-segment elevation acute myocardial infarction: results of a randomized trial. Am Heart J.
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