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Eprosartan

依普沙坦
Mechanism of action:
Eprosartan 是一種血管張力素 II 受體阻斷劑(angiotensin II receptor blocker)。血管張力素 II 與 AT₁ 受體結合時,會引起強烈的血管平滑肌收縮。Eprosartan 則會拮抗 AT₁ 受體,使週邊血管放鬆,週邊阻力下降,降低血管收縮訊號所造成的血流動力學負荷。
Reference(s):
1. Ruilope L et al. (2001). Eprosartan versus enalapril in elderly patients with hypertension: a double-blind, randomized trial. Blood Press.
2. Hedner T et al. (2002). The clinical profile of the angiotensin II receptor blocker eprosartan. J Hypertens Suppl.
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