Aldesleukin

Aldesleukin is a recombinant human interleukin-2 (IL-2) and functions as an immunostimulant. Its mechanism of action involves binding to IL-2 receptors and promoting the proliferation and activation of T cells, B cells, natural killer cells, and macrophages, thereby enhancing the immune system's ability to recognize and attack tumor cells. Because it can trigger intense immune activation, it may cause significant systemic adverse effects, such as capillary leak syndrome, so its clinical use generally requires close medical supervision.