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The Sound of Evolution
Anagliptin
Mechanism of action:
Anagliptin is a DPP-4 inhibitor. By inhibiting DPP-4 enzyme activity, it delays the breakdown of incretins in the body, particularly GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). These incretins stimulate insulin release from pancreatic β cells and suppress glucagon release from pancreatic α cells.
Reference(s):
Zhou Y et al. (2024). TTD: Therapeutic Target Database describing target druggability information. Nucleic Acids Res.
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