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Argatroban


Mechanism of action:

Argatroban is a direct thrombin inhibitor. Argatroban reversibly binds to the active site of thrombin and inhibits thrombin-mediated conversion of fibrinogen into fibrin.

Reference(s):

Tran JQ et al. (1999). Assessment of the potential pharmacokinetic and pharmacodynamic interactions between erythromycin and argatroban. J Clin Pharmacol.

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