Atracurium

Atracurium is a non-depolarizing neuromuscular blocking agent. Atracurium competitively blocks nicotinic acetylcholine receptors (nAChRs) at the motor end-plate, preventing acetylcholine (ACh) from binding to the receptor and opening sodium ion channels. This prevents depolarization and the generation of action potentials. As a result, skeletal muscle contraction is inhibited, leading to muscle relaxation and reduced muscle strength.