top of page
The Sound of Evolution
Aurothioglucose
Mechanism of action:
Aurothioglucose does not have a fully clarified mechanism of action. However, some studies suggest that its gold ion (Au⁺) may bind to sulfhydryl (-SH) groups on adenylyl cyclase, thereby suppressing immune cell metabolism and inflammatory responses.
Reference(s):
1. Botz B et al. (2014). Differential regulatory role of pituitary adenylate cyclase-activating polypeptide in the serum-transfer arthritis model. Arthritis Rheumatol.
2. Shaw CF et al. (1999). Gold-based therapeutic agents. Chem Rev.
bottom of page