The Sound of Evolution
Bemiparin
Mechanism of action:
Bemiparin is a low molecular weight heparin. It mainly acts by binding to antithrombin III and enhancing its activity, thereby inhibiting coagulation factor Xa and reducing the conversion of prothrombin into thrombin, which in turn decreases fibrin formation. In addition, bemiparin also binds to antithrombin III to enhance its activity, thereby lowering the likelihood of thrombus formation and expansion.
Reference(s):
1. Chapman TM et al. (2003). Bemiparin: a review of its use in the prevention of venous thromboembolism and treatment of deep vein thrombosis. Drugs.
2. Planes A et al. (2003). Review of bemiparin sodium—a new second-generation low molecular weight heparin and its applications in venous thromboembolism. Expert Opin Pharmacother.