top of page
< Back

Bromhexine


Mechanism of action:

Bromhexine is a mucolytic agent derived from vasicine, a compound found in Adhatoda vasica. In the body, bromhexine is converted into the active metabolite ambroxol, and it may promote changes in airway secretions and mucus properties, such as mucus viscosity and clearance efficiency. This alters the physical characteristics of high-molecular-weight components in mucus, helping convert highly viscous molecules into lower-molecular-weight substances.

Reference(s):

1. Zanasi A et al. (2017). A reappraisal of the mucoactive activity and clinical efficacy of bromhexine. Multidiscip Respir Med. 


2. Ansarin K et al. (2020). Effect of bromhexine on clinical outcomes and mortality in COVID-19 patients: A randomized clinical trial. Bioimpacts. 


3. Bechgaard E et al. (1982). Bioavailability of bromhexine tablets and preliminary pharmacokinetics in humans. Biopharm Drug Dispos.

bottom of page