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Cefadroxil

Mechanism of action:
Cefadroxil is a first-generation oral cephalosporin antibiotic. The β-lactam ring of Cefadroxil can bind to bacterial penicillin-binding proteins (PBPs), inhibiting their transpeptidase activity and preventing peptidoglycan chains from cross-linking. As a result, the bacterial cell wall becomes structurally weak, and the bacterium eventually undergoes lysis and dies due to osmotic pressure.
Reference(s):
Williamson R et al. (1980). In vivo interaction of beta-lactam antibiotics with the penicillin-binding proteins of Streptococcus pneumoniae. Antimicrob Agents Chemother.
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