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Cefditoren


Mechanism of action:

Cefditoren is a third-generation oral cephalosporin antibiotic. The β-lactam ring of Cefditoren can bind to bacterial penicillin-binding proteins (PBPs), inhibiting their transpeptidase activity and preventing peptidoglycan chains from cross-linking. As a result, the bacterial cell wall becomes structurally weak, and the bacterium eventually undergoes lysis and dies due to osmotic pressure.

Reference(s):

Tempera G et al. (2010). Antibiotic susceptibility of respiratory pathogens recently isolated in Italy: focus on cefditoren. J Chemother.

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