Desflurane

Desflurane is a fluorinated ether derivative. The molecular mechanism of desflurane is not yet fully understood, but like other inhalational anesthetics, it mainly acts through multiple effects on the central nervous system. Desflurane may enhance the activity of GABA_A receptors, increasing chloride influx and leading to neuronal hyperpolarization, which suppresses neuronal excitation and produces sedation and loss of consciousness. Desflurane may also modulate multiple ion channels and synaptic transmission, reducing overall neural network excitability.