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The Sound of Evolution
Docusate
Mechanism of action:
Docusate is a stool softener and a surfactant laxative. It is an anionic surfactant that forms a thin film on the surface of stool, promoting the penetration of water and lipids into the fecal mass, increasing stool water content and softening its texture.
Reference(s):
1. Moriarty KJ et al. (1985). Studies on the mechanism of action of dioctyl sodium sulphosuccinate in the human jejunum. Gut.
2. Tarumi Y et al. (2013). Randomized, double-blind, placebo-controlled trial of oral docusate in the management of constipation in hospice patients. J Pain Symptom Manage.
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