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The Sound of Evolution
Enoxaparin
Mechanism of action:
Enoxaparin is a low molecular weight heparin. It binds to antithrombin III and enhances its inhibitory effect on factor Xa. As a result, factor Xa can no longer convert prothrombin into thrombin, interrupting the downstream formation of fibrin and reducing the likelihood of thrombosis.
Reference(s):
1. Iqbal Z et al. (2011). Enoxaparin: a pharmacologic and clinical review. Expert Opin Pharmacother.
2. Sanderink GJ et al. (2002). Pharmacokinetics and pharmacodynamics of the prophylactic dose of enoxaparin once daily over 4 days in patients with renal impairment. Thromb Res.
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