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The Sound of Evolution
Eprosartan
Mechanism of action:
Eprosartan is an angiotensin II receptor blocker. When angiotensin II binds to the AT₁ receptor, it causes strong contraction of vascular smooth muscle. Eprosartan antagonizes the AT₁ receptor, leading to relaxation of peripheral blood vessels, reduced peripheral resistance, and decreased hemodynamic load caused by vasoconstrictive signaling.
Reference(s):
1. Ruilope L et al. (2001). Eprosartan versus enalapril in elderly patients with hypertension: a double-blind, randomized trial. Blood Press.
2. Hedner T et al. (2002). The clinical profile of the angiotensin II receptor blocker eprosartan. J Hypertens Suppl.
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