top of page
The Sound of Evolution
Etravirine
Mechanism of action:
Etravirine is a non-nucleoside reverse transcriptase inhibitor. Etravirine binds to a hydrophobic allosteric site on viral reverse transcriptase, reducing its activity and thereby decreasing the efficiency of viral reverse transcription.
Reference(s):
1. Berman HM et al. (2000). The Protein Data Bank. Nucleic Acids Res.
2. Zhou Y et al. (2024). TTD: Therapeutic Target Database describing target druggability information. Nucleic Acids Res.
bottom of page