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The Sound of Evolution
Fenoterol
Mechanism of action:
Fenoterol is a short-acting β₂-adrenergic agonist. Fenoterol activates β₂-adrenergic receptors on bronchial smooth muscle, increasing adenylyl cyclase activity and raising intracellular cAMP concentration, which leads to bronchial smooth muscle relaxation.
Reference(s):
1. de Vries B et al. (2001). Effect of fenoterol-induced constitutive beta(2)-adrenoceptor activity on contractile receptor function in airway smooth muscle. Eur J Pharmacol.
2. Boterman M et al. (2006). Protein kinase C potentiates homologous desensitization of the beta2-adrenoceptor in bovine tracheal smooth muscle. Eur J Pharmacol.
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