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The Sound of Evolution
Ibuprofen
Mechanism of action:
Ibuprofen is a propionic acid derivative. Ibuprofen inhibits cyclooxygenase, including COX-1 and COX-2, preventing the conversion of arachidonic acid into prostaglandins and thereby reducing pain, inflammation, and fever.
Reference(s):
1. Zawada ET Jr et al. (1982). Renal consequences of nonsteroidal antiinflammatory drugs. Postgrad Med.
2. Townsend KP et al. (2005). Novel therapeutic opportunities for Alzheimer's disease: focus on nonsteroidal anti-inflammatory drugs. FASEB J.
3. Chen H et al. (2005). Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease. Ann Neurol.
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