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Iprindole


Mechanism of action:

Iprindole is a tricyclic antidepressant and an indole-based tricyclic compound. Its mechanism of action remains unclear, but it is thought to primarily modulate serotonergic neurotransmission in the central nervous system by affecting serotonin receptor-related signaling and thereby influencing mood-related neural functions. Unlike other tricyclic antidepressants, iprindole has only weak inhibitory effects on the reuptake of serotonin (5-HT) and norepinephrine.

Reference(s):

Gluckman MI and Baum T. (1969). The pharmacology of iprindole, a new antidepressant. Psychopharmacologia.

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