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The Sound of Evolution
Meloxicam
Mechanism of action:
Meloxicam is an oxicam derivative. Meloxicam inhibits cyclooxygenase, including COX-1 and COX-2, thereby preventing the conversion of arachidonic acid into prostaglandins and reducing prostaglandin-mediated inflammatory signaling, pain sensitization, and fever responses.
Reference(s):
1. Bekker A et al. (2018). Meloxicam in the management of post-operative pain: Narrative review. J Anaesthesiol Clin Pharmacol.
2. Moore RA et al. (2009). Single dose oral meloxicam for acute postoperative pain in adults. Cochrane Database Syst Rev.
3. Turck D et al. (1996). A review of the clinical pharmacokinetics of meloxicam. Br J Rheumatol.
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