Moexipril

Mechanism of action:
Moexipril is an angiotensin-converting enzyme inhibitor. Moexipril is a prodrug that is converted in the liver into its active metabolite, moexiprilat. Moexiprilat inhibits the activity of angiotensin-converting enzyme, thereby reducing the production of angiotensin II, lowering blood pressure, and decreasing cardiac workload.
Reference(s):
1. Asmar R et al. (2002). Reversal of left ventricular hypertrophy with the ACE inhibitor moexipril in patients with essential hypertension. Acta Cardiol.
2. Blacher J et al. (1998). Increased arterial distensibility in postmenopausal hypertensive women with and without hormone replacement therapy after acute administration of the ACE inhibitor moexipril. Cardiovasc Drugs Ther.
3. Brogden RN et al. (1998). Moexipril. A review of its use in the management of essential hypertension. Drugs.
