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The Sound of Evolution
Moricizine
Mechanism of action:
Moricizine inhibits fast sodium channels on the membranes of cardiac muscle cells, slowing depolarization and reducing myocardial conduction velocity.
Reference(s):
1. Ahmmed GU et al. (2002). Analysis of moricizine block of sodium current in isolated guinea-pig atrial myocytes. Atrioventricular difference of moricizine block. Vascul Pharmacol.
2. Chen X et al. (2002). TTD: Therapeutic Target Database. Nucleic Acids Res.
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