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The Sound of Evolution
Naphazoline
Mechanism of action:
Naphazoline is an imidazoline derivative. Naphazoline activates adrenergic α-receptors, mainly the α₁ receptor. For example, naphazoline can activate α₁ receptors on vascular smooth muscle, causing vasoconstriction and reducing local blood flow.
Reference(s):
1. Vitezic D et al. (1994). Naphazoline nasal drops intoxication in children. Arh Hig Rada Toksikol.
2. Mahieu LM et al. (1993). Imidazoline intoxication in children. Eur J Pediatr.
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