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Nedocromil

Mechanism of action:
Nedocromil is a chromone derivative. Nedocromil inhibits mast cell degranulation, preventing the release of inflammatory mediators such as histamine, leukotrienes, and prostaglandins.
Reference(s):
1. Monteseirin J et al. (2005). L-selectin expression on neutrophils from allergic patients. Clin Exp Allergy.
2. Yazid S et al. (2010). Antiallergic cromones inhibit neutrophil recruitment onto vascular endothelium via annexin-A1 mobilization. Arterioscler Thromb Vasc Biol.
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