top of page
The Sound of Evolution
Netilmicin
Mechanism of action:
Netilmicin is an aminoglycoside antibiotic. Netilmicin irreversibly binds to the 30S ribosomal subunit and disrupts the correct reading of mRNA, causing incorrect amino acids to be incorporated into proteins and producing abnormal or nonfunctional proteins.
Reference(s):
1. Hemsworth S et al. (2005). Once-daily netilmicin for neutropenic pyrexia in paediatric oncology. Acta Paediatr.
2. Klingenberg C et al. (2004). Validation of a simplified netilmicin dosage regimen in infants. Scand J Infect Dis.
3. Brooks JR et al. (2004). Use of once-daily netilmicin to treat infants with suspected sepsis in a neonatal intensive care unit. Biol Neonate.
bottom of page