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Pancrelipase protease
Mechanism of action:
Pancrelipase protease contains multiple enzymes, mainly trypsin, chymotrypsin, elastase, and carboxypeptidase A/B. These enzymes are secreted by the pancreas as inactive zymogens. After entering the duodenum, trypsin is first activated by enteropeptidase, and trypsin then activates the other proteases. These proteases break down dietary proteins into absorbable small peptides and amino acids.
Reference(s):
Schauperl M et al. (2015). Characterizing Protease Specificity: How Many Substrates Do We Need? PLoS One.
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