The Sound of Evolution
Stanozolol
Mechanism of action:
Stanozolol is a 17alpha-alkylated anabolic steroid (17alpha-alkylated anabolic steroid). After entering cells, stanozolol binds to androgen receptors in the cytoplasm, forming a complex that translocates into the nucleus and binds to androgen response elements on DNA. This increases the expression of genes related to protein synthesis, nitrogen retention, and cell growth.
Reference(s):
1. Guilarte M et al. (2008). Acquired angioedema associated with hereditary angioedema due to C1 inhibitor deficiency. J Investig Allergol Clin Immunol.
2. Thevis M et al. (2010). Synthetic anabolic agents: steroids and nonsteroidal selective androgen receptor modulators. Handb Exp Pharmacol.
3. Sloane DE et al. (2007). Hereditary angioedema: Safety of long-term stanozolol therapy. J Allergy Clin Immunol.