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The Sound of Evolution
Tetracycline
Mechanism of action:
Tetracycline is a tetracycline antibiotic. Tetracycline reversibly binds to the 30S subunit of the bacterial ribosome and blocks the binding of aminoacyl-tRNA to the mRNA-ribosome complex, preventing new amino acids from being added to the peptide chain and thereby inhibiting protein synthesis.
Reference(s):
1. Griffin MO et al. (2010). Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature. Am J Physiol Cell Physiol.
2. U.S. FDA. (n.d.). Code of Federal Regulations 216.24: Drug products withdrawn or removed from the market for reasons of safety or effectiveness.
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