top of page
Urofollitropin
Mechanism of action:
Urofollitropin is a human urinary-derived follicle-stimulating hormone. After binding to follicle-stimulating hormone receptors in the ovary or testis, it activates the Gs protein, stimulates adenylyl cyclase, raises intracellular cAMP concentration, and activates protein kinase A. This in turn regulates the transcription of multiple genes related to reproductive cell development, promoting cellular differentiation and functional maturation.
Reference(s):
Goa KL et al. (1998). Follitropin alpha in infertility: a review. BioDrugs.
bottom of page
