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The Sound of Evolution
Guaifenesin/Glyceryl guaiacolate
癒瘡木酚甘油醚
Mechanism of action:
Guaifenesin 目前的分子機制不明，只知道能增加呼吸道分泌物中的水分含量，使濃稠痰液變得較稀薄，降低黏附於呼吸道壁的程度。
Reference(s):
1. Thompson GA et al. (2016). Guaifenesin Pharmacokinetics Following Single-Dose Oral Administration in Children Aged 2 to 17 Years. J Clin Pharmacol.
2. Kagan L et al. (2009). Effect of mode of administration on guaifenesin pharmacokinetics and expectorant action in the rat model. Pulm Pharmacol Ther.
3. Keshavarz M et al. (2013). Anticonvulsant Effect of Guaifenesin against Pentylenetetrazol-Induced Seizure in Mice. Iran J Med Sci.
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