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Methylenedioxymethamphetamine

亞甲二氧甲基苯丙胺

Mechanism of action:

Methylenedioxymethamphetamine 是一種苯乙胺類（phenethylamine）衍生物。Methylenedioxymethamphetamine 會進入神經元並作用於血清素轉運蛋白（serotonin transporter），使其由「回收模式」轉為「反向運輸」，導致大量血清素釋放至突觸間隙。

​Reference(s):

1. Freudenmann RW et al. (2006). The origin of MDMA (ecstasy) revisited: the true story reconstructed from the original documents. Addiction. 


2. Jayanthi LD et al. (2005). Regulation of monoamine transporters: influence of psychostimulants and therapeutic antidepressants. AAPS J. 


3. Verrico CD et al. (2007). MDMA (Ecstasy) and human dopamine, norepinephrine, and serotonin transporters: implications for MDMA-induced neurotoxicity and treatment. Psychopharmacology (Berl).

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