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Pentoxyverine/Carbetapentane citrate

噴托維林
Mechanism of action:
Pentoxyverine 是一種非鴉片類鎮咳劑(non-opioid antitussive agent)。Pentoxyverine 的作用機制尚不清楚,但已知會作用於延腦的咳嗽中樞,提高咳嗽反射閾值,降低對刺激的反應。
Reference(s):
1. Dicpinigaitis PV et al. (2014). Antitussive drugs--past, present, and future. Pharmacol Rev.
2. Brown C et al. (2004). Antitussive activity of sigma-1 receptor agonists in the guinea-pig. Br J Pharmacol.
3. Deisemann H et al. (2008). Effects of common antitussive drugs on the hERG potassium channel current. J Cardiovasc Pharmacol.
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