top of page
< Back

Piperacillin

哌拉西林

Mechanism of action:

Piperacillin 是一種 β-內醯胺類抗生素（β-lactam antibiotic）。Piperacillin 能與青黴素結合蛋白（penicillin-binding proteins，PBPs）結合，抑制肽聚醣（peptidoglycan）交聯，使細胞壁失去結構完整性，最終細菌因無法承受滲透壓而破裂死亡。

​Reference(s):

Lau WK et al. (2006). Randomized, open-label, comparative study of piperacillin-tazobactam administered by continuous infusion versus intermittent infusion for treatment of hospitalized patients with complicated intra-abdominal infection. Antimicrob Agents Chemother.

bottom of page