top of page
The Sound of Evolution
Acetylsalicylic acid
乙醯水楊酸
Mechanism of action:
Acetylsalicylic acid 主要作用機制是不可逆地抑制環氧化酶（cyclooxygenase，COX-1 與 COX-2），進而抑制前列腺素與血栓素（thromboxane A₂）的生成。
Reference(s):
1. Parvez MM et al. (2017). Evaluation of para-Aminosalicylic Acid as a Substrate of Multiple Solute Carrier Uptake Transporters and Possible Drug Interactions with Nonsteroidal Anti-inflammatory Drugs In Vitro. Antimicrob Agents Chemother.
2. Wang C et al. (2014). Aspirin and probenecid inhibit organic anion transporter 3-mediated renal uptake of cilostazol and probenecid induces metabolism of cilostazol in the rat. Drug Metab Dispos.
bottom of page