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Aprotinin

抑肽酶

Mechanism of action:

Aprotinin 是一種絲胺酸蛋白酶抑制劑(serine protease inhibitor)。Aprotinin 能可逆性地抑制多種絲胺酸蛋白酶,包含胰蛋白酶(trypsin)、胰凝乳蛋白酶(chymotrypsin)、激肽釋放酶(kallikrein)、纖溶酶(plasmin)等。主要功能是抑制纖溶酶活性,減少纖維蛋白(fibrin)降解,降低纖溶反應。

​Reference(s):

Aronson JK et al. (2016). Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions (16th ed.). Elsevier Science.

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