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Aurothioglucose

金硫葡萄糖
Mechanism of action:
Aurothioglucose 的作用機制尚未完全明確,不過有些研究認為其金離子(Au⁺)可與腺苷酸環化酶(adenylyl cyclase)的巰基(-SH)結合,進而抑制免疫細胞代謝與發炎反應。
Reference(s):
1. Botz B et al. (2014). Differential regulatory role of pituitary adenylate cyclase-activating polypeptide in the serum-transfer arthritis model. Arthritis Rheumatol.
2. Shaw CF et al. (1999). Gold-based therapeutic agents. Chem Rev.
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