top of page
< Back

Azithromycin

阿奇黴素

Mechanism of action:

Azithromycin 是一種巨環內酯類抗生素（macrolide antibiotic），作用於細菌的 50S 核糖體亞基，與 23S rRNA 上的出口通道鄰近區域結合，阻止肽鏈延長，使細菌的蛋白質合成受抑制，導致細菌生長停滯。

​Reference(s):

1. Noedl H et al. (2006). Azithromycin combination therapy with artesunate or quinine for the treatment of uncomplicated Plasmodium falciparum malaria in adults: a randomized, phase 2 clinical trial in Thailand. Clin Infect Dis. 


2. Peters DH et al. (1992). Azithromycin: a review of its antimicrobial activity, pharmacokinetic properties and clinical efficacy. Drugs. 


3. McMullan BJ et al. (2015). Prescribing azithromycin. Aust Prescr.

bottom of page