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Bemiparin

貝米肝素

Mechanism of action:

Bemiparin 是一種低分子量肝素(low molecular weight heparin)。Bemiparin 主要透過與抗凝血蛋白 III(antithrombin III)結合並增強其活性,抑制凝血因子 Xa(factor Xa),使凝血酶原(prothrombin)變成凝血酶(thrombin)的生成量下降,以減少纖維蛋白(fibrin)形成。此外,bemiparin 也與抗凝血蛋白 III(antithrombin III) 結合,增強其活性,降低血栓形成與擴大的可能性。

​Reference(s):

1. Chapman TM et al. (2003). Bemiparin: a review of its use in the prevention of venous thromboembolism and treatment of deep vein thrombosis. Drugs. 


2. Planes A et al. (2003). Review of bemiparin sodium—a new second-generation low molecular weight heparin and its applications in venous thromboembolism. Expert Opin Pharmacother.

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