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Certoparin

舍托肝素
Mechanism of action:
Certoparin 是一種低分子量肝素(low molecular weight heparin)。Certoparin 會與抗凝血酶 III(antithrombin III)結合,增強對凝血因子 Xa(factor Xa)的抑制作用,使凝血因子 Xa 無法促進凝血酶生成(降低凝血酶原轉化為凝血酶的效率),阻斷了之後纖維蛋白(fibrin)的形成,防止血栓生成。
Reference(s):
Donadini MP et al. (2013). Certoparin for the treatment and prevention of thrombosis: pharmacological profile and results from clinical studies. Expert Opin Drug Metab Toxicol.
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