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Erythromycin

紅黴素

Mechanism of action:

Erythromycin 是一種巨環內酯類抗生素（macrolide antibiotic），作用於細菌的 50S 核糖體亞基，與 23S rRNA 鄰近肽鏈出口通道的區域結合，阻止轉位（translocation）與肽鏈延長，使細菌的蛋白質合成無法進行，導致細菌生長停滯。

​Reference(s):

1. Kanazawa S et al. (2001). The effects of grapefruit juice on the pharmacokinetics of erythromycin. Eur J Clin Pharmacol. 


2. Ogwal S et al. (2001). Bioavailability and stability of erythromycin delayed release tablets. Afr Health Sci. 


3. Okudaira T et al. (2007). Effect of the treatment period with erythromycin on cytochrome P450 3A activity in humans. J Clin Pharmacol.

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