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Fenoterol

非諾特羅
Mechanism of action:
Fenoterol 是一種 β₂ 腎上腺素受體促效劑(short-acting β₂-adrenergic agonist)。Fenoterol 能活化支氣管平滑肌的 β₂ 腎上腺素受體,促進腺苷酸環化酶(adenylyl cyclase)活性上升,使細胞內 cAMP 濃度增加,導致支氣管平滑肌放鬆。
Reference(s):
1. de Vries B et al. (2001). Effect of fenoterol-induced constitutive beta(2)-adrenoceptor activity on contractile receptor function in airway smooth muscle. Eur J Pharmacol.
2. Boterman M et al. (2006). Protein kinase C potentiates homologous desensitization of the beta2-adrenoceptor in bovine tracheal smooth muscle. Eur J Pharmacol.
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