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Fluphenazine

氟奮乃靜

Mechanism of action:

Fluphenazine 是一種啡噻𠯤類（phenothiazine）衍生物。Fluphenazine 主要在中腦邊緣通路（mesolimbic pathway）阻斷多巴胺 D₂ 受體。

​Reference(s):

1. Seeman P et al. (2002). Atypical antipsychotics: mechanism of action. Can J Psychiatry. 


2. Hoyberg OJ et al. (1993). Risperidone versus perphenazine in the treatment of chronic schizophrenic patients with acute exacerbations. Acta Psychiatr Scand. 


3. Qin ZH et al. (1994). Dopamine receptor blockade increases dopamine D2 receptor and glutamic acid decarboxylase mRNAs in mouse substantia nigra. Eur J Pharmacol.

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