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Follitropin alfa
阿法重組濾泡刺激激素
Mechanism of action:
Follitropin alfa 是一種重組人類濾泡刺激素(recombinant human follicle-stimulating hormone)。當 follitropin alfa 與卵巢或睪丸中的促卵泡激素受體(follicle-stimulating hormone receptor)結合後,啟動 Gs 蛋白,活化腺苷酸環化酶(adenylate cyclase),使 cAMP 上升,促進與生殖細胞發育相關的訊號與基因表達。
Reference(s):
Goa KL et al. (1998). Follitropin alpha in infertility: a review. BioDrugs.
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