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Meloxicam

美洛昔康

Mechanism of action:

Meloxicam 是一種昔康類（oxicam）衍生物。Meloxicam 能抑制環氧化酶（cyclooxygenase），包含 COX-1 與 COX-2，阻止將花生四烯酸（arachidonic acid）轉換為前列腺素（prostaglandin），降低前列腺素介導的發炎訊號、疼痛敏感化與發燒反應。

​Reference(s):

1. Bekker A et al. (2018). Meloxicam in the management of post-operative pain: Narrative review. J Anaesthesiol Clin Pharmacol. 


2. Moore RA et al. (2009). Single dose oral meloxicam for acute postoperative pain in adults. Cochrane Database Syst Rev. 


3. Turck D et al. (1996). A review of the clinical pharmacokinetics of meloxicam. Br J Rheumatol.

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