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Methoxyflurane

甲氧氟醚
Mechanism of action:
Methoxyflurane 是一種氟化醚類(fluorinated ether)衍生物。Methoxyflurane 的受體機制尚未完全明確,但已知可增強 GABA_A 與 glycine 受體的抑制性作用,提高神經元對抑制性訊號的反應,降低中樞神經系統的興奮程度。
Reference(s):
1. Moody EJ et al. (1988). Modulation of the benzodiazepine/gamma-aminobutyric acid receptor chloride channel complex by inhalation anesthetics. J Neurochem.
2. Martin DC et al. (1995). Volatile anesthetics and glutamate activation of N-methyl-D-aspartate receptors. Biochem Pharmacol.
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