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Moexipril

莫昔普利

Mechanism of action:

Moexipril 是一種血管張力素轉化酶抑制劑（angiotensin-converting enzyme inhibitor）。Moexipril 為前軀藥，在肝臟轉化為活性代謝物 moexiprilat。Moexiprilat 能抑制血管張力素轉化酶（angiotensin-converting enzyme）的活性，因而減少血管張力素 II（angiotensin II）的生成，使血壓下降、心臟負荷減輕。

​Reference(s):

1. Asmar R et al. (2002). Reversal of left ventricular hypertrophy with the ACE inhibitor moexipril in patients with essential hypertension. Acta Cardiol. 


2. Blacher J et al. (1998). Increased arterial distensibility in postmenopausal hypertensive women with and without hormone replacement therapy after acute administration of the ACE inhibitor moexipril. Cardiovasc Drugs Ther. 


3. Brogden RN et al. (1998). Moexipril. A review of its use in the management of essential hypertension. Drugs.

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