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Netilmicin

奈替米星

Mechanism of action:

Netilmicin 是一種胺基醣苷類抗生素（aminoglycoside antibiotic）。Netilmicin 能不可逆地結合於 30S 核糖體亞基，影響 mRNA 的正確解讀，導致錯誤胺基酸被摻入蛋白質，生成異常或無功能蛋白質。

​Reference(s):

1. Hemsworth S et al. (2005). Once-daily netilmicin for neutropenic pyrexia in paediatric oncology. Acta Paediatr. 


2. Klingenberg C et al. (2004). Validation of a simplified netilmicin dosage regimen in infants. Scand J Infect Dis. 


3. Brooks JR et al. (2004). Use of once-daily netilmicin to treat infants with suspected sepsis in a neonatal intensive care unit. Biol Neonate.

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