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Pancrelipase lipase
胰液分解酶-脂酶
Mechanism of action:
Pancreatic lipase 能將三酸甘油脂(triglyceride)水解為 2-單酸甘油脂(2-monoglyceride)、游離脂肪酸(free fatty acids)等,再與膽鹽(bile salts)形成混合膠束(mixed micelle),這些結構才能穿過小腸刷狀緣進入腸上皮細胞。輔脂酶(colipase)能幫助 pancreatic lipase 在膽鹽存在下穩定附著於脂肪表面。
Reference(s):
1. Chapus C et al. (1988). Minireview on pancreatic lipase and colipase. Biochimie.
2. Chapus C et al. (1976). Mechanism of pancreatic lipase action. 1. Interfacial activation of pancreatic lipase. Biochemistry.
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