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Phenazopyridine

非那吡啶

Mechanism of action:

Phenazopyridine 是一種偶氮染料類（azo dye）衍生物。Phenazopyridine 的確切作用機制尚未釐清，但已知經腎臟排泄後，在膀胱與尿道黏膜表面能降低感覺神經刺激與疼痛感受，減少發炎或刺激狀態下，泌尿道黏膜對排尿時機械與化學刺激的敏感性。

​Reference(s):

1. Shore SN et al. (2019). Safety analysis of long-term phenazopyridine use for radiation cystitis. J Oncol Pharm Pract. 


2. Suter DM et al. (2009). Phenazopyridine induces and synchronizes neuronal differentiation of embryonic stem cells. J Cell Mol Med. 


3. Rehfuss A et al. (2018). Phenazopyridine: A Preoperative Way to Identify Ureteral Orifices. Urology.

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